COA7 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52496
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | beta-lactamase hcp-like protein,C1orf163,Chromosome 1 open reading frame 163,FLJ12439,Hcp beta lactamase like protein C1orf163,Hypothetical protein LOC65260,RESA1,Sel1 repeat containing 1,sel1 repeat-containing protein 1,COA7抗体 |
| Swissprot | Q96BR5 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. COA7 (cytochrome c oxidase assembly factor 7), also known as RESA1, SELRC1 or C1orf163, is a 231 amino acid mitochondrial protein that belongs to the hcp beta-lactamase family. Consisting of five Sel1-like repeats, COA7 may be associated with respiratory chain assembly. COA7 is encoded by a gene located on human chromosome 1p32.3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene, which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. |
Images
Western blot analysis of HEPG2 and HL-60 cell lysates using COA7 Polyclonal Antibody at dilution of 1:550
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using COA7 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using COA7 Polyclonal Antibody at dilution of 1:55(×200)
