Complement C3 Polyclonal Antibody(Capture/Detector)
| 规格： | / 25μg / 100μg |
| 价格： | / ￥800 / ￥2100 |
货号：AN000660P
货期：咨询
宿主: Rabbit
反应性: Pg
应用: ELISA Capture/Detector
Overview
| Synonyms | ASP;CPAMD1;AHUS5;ARMD9;C3a;C3b; |
| Swissprot | P01025 |
| Source | Rabbit |
| Reactivity | Pig |
| Immunogen | Recombinant Pig Complement C3 protein expressed by E.coli |
| Application | ELISA Capture/Detector |
| Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS,pH 7.4 |
| Background | The complement system is an important effector which bridges the innate and adaptive immune systems . The third component of complement, C3, plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. Human C3, composed of α and β chains (115 and 75 kDa, respectively). Activation of C3 convertase cleaves the C3 α-subunit to generate C3a, which acts as an anaphylatoxin to mediate the local inflammatory response. C3b is further cleaved into iC3b, C3c, C3dg, and C3f. |
