Complement Factor H/CFH Polyclonal Antibody(Capture/Detector)
| 规格: | / 25μg / 100μg |
| 价格: | / ¥800 / ¥2100 |
货号:AN000540P
货期:咨询
宿主: Rabbit
反应性: H
应用: ELISA Capture/Detector
Overview
| Synonyms | CF-H;AHUS1;AMBP1;FH;FHL1;ARMD4;ARMS1;CFHL3;HF;HF1;HF2;HUS; |
| Swissprot | P08603 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human Complement Factor H/CFH protein expressed by Mammalian |
| Application | ELISA Capture/Detector |
| Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS,pH 7.4 |
| Background | Complement factor H (CFH) is an abundant plasma glycoprotein that regulates the function of the alternative complement pathway in fluid phase and on cellular surfaces. Factor H binds to C3b,accelerates the decay of the alternative pathway C3-convertase (C3bBb) and acts as a cofactor for the factor I-mediated proteolytic inactivation of C3b. It plays a critical role in the homeostasis of the complement system in plasma and in the protection of bystander host cells and tissues from damage by complement activation. Abnormalities in factor H have been associated with renal disease. |
