Connexin-26 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12460
宿主: Rabbit
反应性: H,R
应用: IHC
Overview
| Synonyms | connexin 26,Connexin-26,Cx26,CXB2,DFNA3,DFNB1,Gap junction beta-2 protein,GJB2,HID,KID,NSRD1,PPK,GJB2抗体 |
| Swissprot | P29033 |
| Source | Rabbit |
| Reactivity | Human,Rat |
| Immunogen | Synthetic peptide of human GJB2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 2.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Cell junction>gap junction. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. |
