Connexin 43 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70097
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Connexin 43,Connexin-43,Cx 43,Cx43,CXA1,DFNB38,Gap junction 43 kDa heart protein,Gap junction alpha-1 protein,Gap junction protein alpha 1 43kDa (connexin 43),Gap junction protein alpha 1 43kDa,Gap junction protein alpha like,GJA 1,Gja1,GJAL,ODD,ODDD,ODOD,SDTY3,Connexin 43抗体 |
| Swissprot | P17302,P23242,P08050 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:2000;IHC,,1:300-1:800; |
| Concentration | 0.53 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Cell junction>gap junction. |
| Tissue specificity | Expressed in the heart and fetal cochlea.Highest expression level in pigmented layer of retina |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. |
Images
Western Blot analysis of various samples using Connexin 43 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse heart using Connexin 43 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat heart using Connexin 43 Polyclonal Antibody at dilution of 1:300.
