COPS5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10415
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | 38 kDa Mov34 homolog,COP9 (constitutive photomorphogenic) homolog subunit 5,COP9 constitutive photomorphogenic homolog subunit 5,COP9 signalosome complex subunit 5,COP9 signalosome subunit 5,Cop9 subunit 5,COPS 5,cops5,CSN 5,CSN5,CSN5,JAB 1,Jun activation domain binding protein 1,Jun activation domain binding protein,Jun activation domain-binding protein 1,MGC3149,MOV 34,MOV34,MOV34 family,38-KD member,SGN 5,SGN5,Signalosome subunit 5,COPS5抗体 |
| Swissprot | Q92905 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human COPS5 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:150-1:500; |
| Concentration | 0.9 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors |
