COX17 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19376
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | COX 17,COX17,COX17 cytochrome c oxidase assembly homolog (S. cerevisiae),COX17 cytochrome c oxidase assembly homolog,COX17 homolog cytochrome c oxidase assembly protein,COX17,cytochrome c oxidase assembly protein cox17 homolog,Cytochrome c oxidase copper chaperone,Human homolog of yeast mitochondrial copper recruitment,MGC104397,MGC117386,OTTHUMP00000215284,OTTHUMP00000215285,COX17抗体 |
| Swissprot | Q14061 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human COX17 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 1.2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion intermembrane space. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen.This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes.The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex.This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme.This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins.This gene is no longer considered to be a candidate gene for COX deficiency.A pseudogene COX17P has been found on chromosome 13. |
