CRISP3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11104
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Aeg 2,Aeg2,CRIS3,CRISP 3,CRISP-3,Crisp3,CRS 3,CRS3,Cysteine rich secretory protein 3,Cysteine-rich secretory protein 3,dJ442L6.3,MGC126588,OTTHUMP00000016590,OTTHUMP00000039911,SGP 28,SGP28,SGP28 protein,Specific granule protein (28 kDa),Specific granule protein of 28 kDa,CRISP3抗体 |
| Swissprot | P54108 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human CRISP3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. In neutrophils, localized in specific granules. |
| Tissue specificity | Salivary gland, pancreas and prostate > epididymis, ovary, thymus and colon. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. AEG is a sperm surface protein involved in the fusion of egg and sperm. Although CRISP-1 (also designated AEG-like protein, ARP, cysteine-rich secretory protein-1 or AEG-related protein) is not the ortholog of rodent AEG, it resembles AEG in that it is an epididymal secretory glycoprotein that binds to the postacrosomal region of the sperm head. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva. |
