CSRP3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18409
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | cardiac,Cardiac LIM protein,CLP,CMD1M,CMH12,CRP3,Csrp3,CSRP3,Cysteine and glycine-rich protein 3,Cysteine rich protein 3,Cysteine-rich protein 3,LIM domain only 4 ,LIM domain protein,LMO4,MLP,Muscle LIM protein,CSRP3抗体 |
| Swissprot | P50461 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 1.3mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Cytoplasm>cytoskeleton. Cytoplasm>myofibril>sarcomere>Z line. Mainly cytoplasmic (By similarity). In the nucleus it associates with the actin cytoskeleton (Potential). In the Z line, found associated with GLRX3. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. |
Images
Western blot analysis of Human heart tissue Rat heart tissue and Mouse heart tissue lysates using CSRP3 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human brain tissue using CSRP3 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSRP3 Polyclonal Antibody at dilution of 1:40(×200)
