CST3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40453
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | AD8, Amyloid angiopathy and cerebral hemorrhage, ARMD11, CST3 protein, Cystatin 3, CystatinC, Epididymis secretory protein Li 2, bA218C14.4, Gamma trace, HCCAA, HEL S 2, Neuroendocrine basic polypeptide, Post gamma globulin,CST3抗体 |
| Swissprot | P01034 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Human Cystatin-C protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB 1:2000-1:4000 IHC 1:100-1:300 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Amyloid, Secreted |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration,shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions,establishing its role in vascular disease. In addition,this protein has been shown to have an antimicrobial function,inhibiting the replication of herpes simplex virus. |
Images
Western Blot analysis of Caco-2 cells using CST3 Polyclonal Antibody at dilution of 1:3000.
Immunohistochemistry of paraffin-embedded Human kidney using CST3 Polycloanl Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Mouse kidney using CST3 Polycloanl Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Rat kidney using CST3 Polycloanl Antibody at dilution of 1:200.
