CUEDC2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14902
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | bA18I14.5,C10orf66,Chromosome 10 open reading frame 66,CUE domain containing 2,CUE domain-containing protein 2,CUED2,CUED2,Cuedc2,MGC2491,OTTHUMP00000020368,CUEDC2抗体 |
| Swissprot | Q9H467 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human CUEDC2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. |
| Tissue specificity | Significantly up-regulated in breast tumor tissues compared with matched adjacent normal tissues (at protein level). Levels inversely correlate with ESR1 in breast cancers and are lower in low-grade tumors compared to high-grade tumors. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | CUEDC2 is involved in ubiquitin- and proteasome-mediated degradation of progesterone receptor and estrogen receptor (ER)-alpha.CUEDC2 reduced PRB protein content and promoted progesterone-induced PRB degradation via the ubiquitin-proteasome pathway. |
Images
Western Blot analysis of Human breast infiltRative duct and fetal brain tissue, Mouse brain tissue using CUEDC2 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human breast cancer using CUEDC2 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human gastric cancer using CUEDC2 Polyclonal Antibody at dilution of 1:50
