CXCL5/LIX Polyclonal Antibody(Capture/Detector)
| 规格： | / 25μg / 100μg |
| 价格： | / 询价 / 询价 |
货号：AN003830P
货期：咨询
宿主: Rabbit
反应性: R
应用: ELISA Capture/Detector
Overview
| Synonyms | Scyb;Small-inducible cytokine B;Cxcl;Cytokine LIX;LIX;Small-inducible cytokine B5;Scyb5;Cxcl5;Scyb5 |
| Swissprot | P97885 |
| Source | Rabbit |
| Reactivity | Rat |
| Immunogen | Recombinant Rat CXCL5/LIX Protein expressed by E.coli |
| Application | ELISA Capture/Detector |
| Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS ,pH 7.4 |
| Background | LPS-induced CXC chemokine (LIX) is a chemokine similar to two human chemokines, ENA-78 (CXCL5) and GCP-2 (CXCL6). LIX can be produced by many immune cells, such as macrophages, eosinophils , as well as non-immune cells including mesothelial cells, and fibroblasts. Increased serum LIX has been observed in obesity and insulin resistance in mice and humans and is associated with complications of diabetes including nephropathy and atherosclerosis. It is mainly produced when induced by LPS, IL-17 and/or TNF-α. According to the previous studies, cancer cell autonomous secretion of LIX as sufficient to drive infiltration of mature, protumorigenic neutrophils in a mouse model of non-small cell lung cancer (NSCLC). |
