CYP11B2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17738
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | ALDOS,Aldosterone synthase,Aldosterone-synthesizing enzyme,C11B2,CYP11B2,CYPXIB2,Cytochrome P-450Aldo,Cytochrome P-450C18,Cytochrome P450 11B2,Cytochrome P450 11B2, mitochondrial,mitochondrial,P-450Aldo,P-450C18,Steroid 18-hydroxylase,CYP11B2抗体 |
Swissprot | P19099 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human CYP11B2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. |