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CYP11B2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17738

宿主: Rabbit

反应性: H

应用: WB,IHC

  • 详情
  • Overview

    Synonyms ALDOS,Aldosterone synthase,Aldosterone-synthesizing enzyme,C11B2,CYP11B2,CYPXIB2,Cytochrome P-450Aldo,Cytochrome P-450C18,Cytochrome P450 11B2,Cytochrome P450 11B2, mitochondrial,mitochondrial,P-450Aldo,P-450C18,Steroid 18-hydroxylase,CYP11B2抗体
    Swissprot P19099
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human CYP11B2
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:50-1:300;
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
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