CYP1A1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14029
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | AHH,AHRR,Aryl hydrocarbon hydroxylase,CP11,CP1A1,CYP 1,CYP1,cyp1a1,CYPIA1,Cytochrome P1 450 dioxin inducible,Cytochrome P1-450,Cytochrome P450 1A1,Cytochrome P450 family 1 subfamily A polypeptide 1,Cytochrome P450 form 6,Cytochrome P450 subfamily I (aromatic compound inducible) polypeptide 1,Cytochrome P450-C,Cytochrome P450-P1,Flavoprotein-linked monooxygenase,Microsomal monooxygenase,P1 450,P450 C,P450 form 6,P450 P1,P450DX,Xenobiotic monooxygenase,CYP1A1抗体 |
| Swissprot | P04798 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human CYP1A1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endoplasmic reticulum membrane. Microsome membrane. |
| Tissue specificity | Lung, lymphocytes and placenta. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. |
