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CYP27A1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-11121

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms 12-alpha-triol 27-hydroxylase,5-beta-cholestane-3-alpha,5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase,5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase,5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase,7-alpha,Cholestanetriol 26 monooxygenase,CP27,CP27A,CTX,CYP,CYP27,CYP27A1,Cytochrome P 450C27/25,Cytochrome P-450C27/25,Cytochrome P450 27,Cytochrome P450 27 mitochondrial,Cytochrome P450 family 27 subfamily A member 1,Cytochrome P450 family 27 subfamily A polypeptide 1,Cytochrome P450 subfamily XXVIIA (steroid 27-hydroxylase cerebrotendinous xanthomatosis) polypeptide 1,mitochondrial,Sterol 26 hydroxylase,Sterol 26 hydroxylase mitochondrial,Sterol 26-hydroxylase,Sterol 27 hydroxylase,Sterol 27-hydroxylase,Vitamin D(3) 25 hydroxylase,Vitamin D(3) 25-hydroxylase,CYP27A1抗体
    Swissprot Q02318
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human CYP27A1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 0.6 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.
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