CYP2B6 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16374
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | 1,4 cineole 2 exo monooxygenase,11B1,CP2B6,CPB 6,CPB6,CYP 2B6,CYP IIB6,CYP2B,CYP2B6,CYP2B7,CYP2B7P,CYPIIB6,Cytochrome P450 2B6,Cytochrome P450 family 2 subfamily B,Cytochrome P450 family 2 subfamily B polypeptide 6,Cytochrome P450 IIB1,Cytochrome P450 phenobarbital inducible,Cytochrome P450 subfamily IIB (phenobarbital inducible),Cytochrome P450 subfamily IIB (phenobarbital inducible) polypeptide 6,Cytochrome P450 subfamily IIB polypeptide 6,EFVM,IIB1,P450,P450 IIB1,P450IIB1,CYP2B6抗体 |
| Swissprot | P20813 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human CYP2B6 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:200-1:1000; |
| Concentration | 1.2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endoplasmic reticulum membrane. Microsome membrane. |
| Tissue specificity | Expressed in liver, lung and heart right ventricle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. |
