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DCBLD2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14932

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms 1700055P21Rik,AW146002,CLCP1,coagulation factor V/VIII-homology domains protein 1,CUB and LCCL domain-containing protein 2,CUB,CUB,LCCL and coagulation factor V/VIII-homology domains protein 1,DCBD2,DCBLD2,Discoidin,discoidin CUB and LCCL domain containing 2,Discoidin,CUB and LCCL domain-containing protein 2,Endothelial and smooth muscle cell-derived neuropilin-like protein,ESDN,LCCL and coagulation factor V/VIII-homology domains protein 1,DCBLD2抗体
    Swissprot Q96PD2
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human DCBLD2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:100-1:300
    Concentration 0.2 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Tissue specificity Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background CLCP1 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1), also known as DCBLD2 (discoidin, CUB and LCCL domain containing 2) or ESDN, is a 775 amino acid single-pass type I membrane protein that contains one CUB domain, one LCCL domain and one F5/8 type C domain. Expressed at high levels in heart, testis and skeletal muscle, CLCP1 is thought to regulate vascular smooth muscle cell (VSMC) proliferation and remodeling and may be involved in the transformation and metastasis of various cancers, such as metastatic lung cancer and gastric carcinoma.
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