DDAH1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16196
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | DDAH,DDAH I,DDAH-1,DDAH1,DDAH1,DDAHI,Dimethylargininase 1,Dimethylargininase-1,Dimethylarginine dimethylaminohydrolase 1,N(G),N(G)-dimethylarginine dimethylaminohydrolase 1,NG NG dimethylarginine dimethylaminohydrolase,DDAH1抗体 |
| Swissprot | O94760 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human DDAH1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Extracellular region or secreted,extracellular exosome,Mitochondrion |
| Tissue specificity | Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues. |
