DDC Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19409
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | AADC,Aromatic L Amino Acid Decarboxylase,Aromatic-L-amino-acid decarboxylase,DDC,DDC_HUMAN,DOPA decarboxylase (aromatic L-amino acid decarboxylase),DOPA decarboxylase,DDC抗体 |
Swissprot | P20711 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human DDC |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
Concentration | 1.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytosol,Extracellular region or secreted,Other locations |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |