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DDC Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19409

宿主: Rabbit

反应性: H

应用: WB,IHC

  • 详情
  • Overview

    Synonyms AADC,Aromatic L Amino Acid Decarboxylase,Aromatic-L-amino-acid decarboxylase,DDC,DDC_HUMAN,DOPA decarboxylase (aromatic L-amino acid decarboxylase),DOPA decarboxylase,DDC抗体
    Swissprot P20711
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human DDC
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:25-1:100;
    Concentration 1.5mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytosol,Extracellular region or secreted,Other locations
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
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