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Desmin Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70179

宿主: Rabbit

反应性: M,R

应用: WB,IHC

  • 详情
  • 文献(1)
  • Overview

    Synonyms CMD1I,CSM1,CSM2,DES,DESM,Desmin,FLJ12025,FLJ39719,FLJ41013,FLJ41793,Intermediate filament protein,OTTHUMP00000064865,Desmin抗体
    Swissprot P31001,P48675
    Source Rabbit
    Reactivity Mouse,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse desmin
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:1000-1:2000;IHC,,1:500-1:1000;
    Concentration 2 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane, Cytoplasm, Intermediate filament, Membrane, Nucleus
    Tissue specificity Cardiac progenitor cells and immature cardiomyocytes (at protein level).Highest expression level in skeletal muscle tissue.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
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