DIABLO Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14352
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | 0610041G12Rik,DBLOH,DBOH,DFNA64,diablo,Diablo homolog (Drosophila),Diablo homolog,Diablo homolog mitochondrial,Diablo IAP binding mitochondrial protein,Diablo like protein,DIABLO S,Direct IAP binding protein with low pI,Direct IAP-binding protein with low pI,FLJ10537,FLJ25049,mitochondrial,Mitochondrial Smac protein,Second mitochondria derived activator of caspase,Second mitochondria-derived activator of caspase,SMAC 3,Smac,Smac protein,SMAC3,DIABLO抗体 |
| Swissprot | Q9NR28 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human DIABLO |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion. Released into the cytosol when cells undergo apoptosis. |
| Tissue specificity | Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes. Isoform 3 is ubiquitously expressed. |
Images
Western Blot analysis of Lncap, SKOV3, MCF7 and 293T cell using DIABLO Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human colon cancer using DIABLO Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer using DIABLO Polyclonal Antibody at dilution of 1:50
