DIO1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11137
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | BYE 1,BYE1,C20orf158,DATF 1,DATF-1,Death associated transcription factor 1,Death inducer obliterator 1,Death-associated transcription factor 1,Death-inducer obliterator 1,DIDO 1,DIDO 2,DIDO 3,DIDO1,DIDO1,DIDO2,DIDO3,DIO 1,DIO-1,DIO1,dJ885L7.8,DKFZp434P1115,FLJ11265,hDido 1,hDido1,KIAA0333,MGC16140,DIDO1抗体 |
| Swissprot | Q9BTC0 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human DIDO1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Translocates to the nucleus after pro-apoptotic stimuli. |
| Tissue specificity | Ubiquitous. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. |
