DKK2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10286
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | Dickkopf 2,Dickkopf gene 2 ,Dickkopf homolog 2,Dickkopf related protein 2,Dickkopf WNT signaling pathway inhibitor 2,Dickkopf-2,Dickkopf-related protein 2,Dickkopf2,DKK 2,Dkk-2,Dkk2,DKK2,hDkk 2,hDkk-2,hDkk2,DKK2抗体 |
| Swissprot | Q9UBU2 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human DKK2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Tissue specificity | Expressed in heart, brain, skeletal muscle and lung. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). |
