DMBT1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40467
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Apactin, CRP, Crpd, DBMT1, Deleted in malignant brain tumors 1 protein, DMBT1, DMBT1 prototype precursor, Ebnerin, FLJ61058, Glycoprotein 300, Glycoprotein 340, GP340, Gp340 variant protein, GP340, Hensin, MGC164738, Muclin, p80, Pancrin, SAG, Salivary agglutinin, Surfactant pulmonary associated D binding protein, Vomeroglandin,DMBT1抗体 |
| Swissprot | Q9UGM3 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Human Deleted in malignant brain tumors 1 protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:500 |
| Concentration | 0.71mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. |
Images
Immunohistochemistry of paraffin-embedded Human lung using DMBT1 Polycloanl Antibody at dilution of 1:300.
Immunohistochemistry of paraffin-embedded Human duodenal cancer using DMBT1 Polycloanl Antibody at dilution of 1:300.
Immunohistochemistry of paraffin-embedded Mouse lung using DMBT1 Polycloanl Antibody at dilution of 1:300.
Immunohistochemistry of paraffin-embedded Rat lung using DMBT1 Polycloanl Antibody at dilution of 1:300.
