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DNAJC2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17815

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms AU020218,DnaJ (Hsp40) homolog subfamily C member 2,DnaJ homolog subfamily C member 2,Dnajc2,DNJC2,M phase phosphoprotein 11,M-phase phosphoprotein 11,MGC105894,MIDA1,MPHOSPH11,MPP11,OTTMUSP00000031226,ZRF1,Zrf2,ZUO1,Zuotin related factor 1,Zuotin related factor 2,Zuotin-related factor 1,DNAJC2抗体
    Swissprot Q99543
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human DNAJC2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 1.2mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus. Cytoplasm>cytosol.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene is a member of the M-phase phosphoprotein (MPP) family.The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol.The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome.This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts.Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors.This gene has a pseudogene on chromosome 6.Alternatively spliced variants which encode different protein isoforms have been described.
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