DNAJC2 Polyclonal Antibody
| 规格: | / 20μL / 60μL / 120μL / 200μL |
| 价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17815
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | AU020218,DnaJ (Hsp40) homolog subfamily C member 2,DnaJ homolog subfamily C member 2,Dnajc2,DNJC2,M phase phosphoprotein 11,M-phase phosphoprotein 11,MGC105894,MIDA1,MPHOSPH11,MPP11,OTTMUSP00000031226,ZRF1,Zrf2,ZUO1,Zuotin related factor 1,Zuotin related factor 2,Zuotin-related factor 1,DNAJC2抗体 |
| Swissprot | Q99543 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human DNAJC2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 1.2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm>cytosol. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene is a member of the M-phase phosphoprotein (MPP) family.The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol.The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome.This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts.Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors.This gene has a pseudogene on chromosome 6.Alternatively spliced variants which encode different protein isoforms have been described. |
