DNM1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-15607
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | B dynamin,D100,DNM 1,DNM,DNM1,DYN1,Dynamin,Dynamin-1,Dynamin1,DNM1抗体 |
Swissprot | Q05193 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human DNM1 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Cytoplasm>cytoskeleton. Microtubule-associated. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. |