DNMT1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70196
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | ADCADN,AIM,CXXC finger protein 9,CXXC-type zinc finger protein 9,CXXC9,DNA (cytosine 5 ) methyltransferase 1,DNA (cytosine-5)-methyltransferase 1,DNA methyltransferase 1,DNA methyltransferase HsaI,DNA methyltransferase M.HsaI.,DNA MTase,DNA MTase HsaI,DNMT 1,DNMT,Dnmt1,DNMT1,Dnmt1o,FLJ16293,HSN1E,M.HsaI,MCMT,Met1,MGC104992,mMmul,MommeD2,DNMT1抗体 |
| Swissprot | P26358 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Dnmt1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 0.72 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Ubiquitous; highly expressed in fetal tissues, heart, kidney, placenta, peripheral blood mononuclear cells, and expressed at lower levels in spleen, lung, brain, small intestine, colon, liver, and skeletal muscle. Isoform 2 is less expressed than isoform 1. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. |
Images
Immunohistochemistry analysis of paraffin-embedded human liver cancer using DNMT1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human kidney using DNMT1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using DNMT1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human breast cancer using DNMT1 Polyclonal Antibody at dilution of 1:300.
