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DRD1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-15589

宿主: Rabbit

反应性: H

应用: WB

  • 详情
  • Overview

    Synonyms D(1A) dopamine receptor,D1A dopamine receptor,DADR,Dopamine D1 receptor,dopamine receptor D1,DR D1,DR D1A,DRD 1,DRD 1A,DRD1,DRD1,DRD1A,DRD1抗体
    Swissprot P21728
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human DRD1
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.2 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane. Endoplasmic reticulum membrane. Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14.
    Tissue specificity Detected in caudate, nucleus accumbens and in the olfactory tubercle.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
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