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DTNB Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14963

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms Beta dystrobrevin,Beta-dystrobrevin,DTN B,DTN-B,Dtnb,DTNB,Dystrobrevin beta,MGC17163,MGC57126,DTNB抗体
    Swissprot O60941
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human DTNB
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 1.1 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm.
    Tissue specificity Highly expressed in brain, kidney and pancreas.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
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