DUSP26 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11170
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | DSP-4,Dual specificity phosphatase 26 (putative),Dual specificity phosphatase 26,Dual specificity phosphatase SKRP3,Dual specificity protein phosphatase 26,DUS26,DUSP24,DUSP26,Hypothetical protein FLJ31142,LDP 4,LDP-4,Low molecular mass dual specificity phosphatase 4,Low-molecular-mass dual-specificity phosphatase 4,MAP kinase phosphatase 8,MGC1136,MGC2627,Mitogen activated protein kinase phosphatase 8,Mitogen-activated protein kinase phosphatase 8,MKP-8,MKP8,NATA1,NATA1 protein,Novel amplified gene in thyroid anaplastic cancer,SKRP3,DUSP26抗体 |
| Swissprot | Q9BV47 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human DUSP26 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Golgi apparatus. |
| Tissue specificity | Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma. |
