DYNLL1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11159
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 8 kDa dynein light chain,8kDLC,Cytoplasmic dynein light polypeptide,DLC1,DLC8,DNCL1,DNCLC1,DYL1,Dynein,cytoplasmic,light chain 1,Dynein light chain 1 cytoplasmic,Dynein light chain 1,cytoplasmic,Dynein light chain LC8 type 1,Dynein light chain LC8-type 1,Dynein,cytoplasmic,light polypeptide 1,Dynein,light chain,LC8-type 1,DYNLL1,HDLC1,LC8,LC8a,MGC126137,MGC126138,MGC72986,PIN,Protein inhibitor of neuronal nitric oxide synthase,Protein inhibitor of neuronal NOS,DYNLL1抗体 |
| Swissprot | P63167 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human DYNLL1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, cytoskeleton. Nucleus. Mitochondrion. Upon induction of apoptosis translocates together with BCL2L11 to mitochondria. |
| Tissue specificity | Ubiquitous. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. |
Images
Western Blot analysis of Mouse brain tissue using DYNLL1 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human prostate cancer using DYNLL1 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human brain using DYNLL1 Polyclonal Antibody at dilution of 1:25
