EAAT3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17312
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | EAA3,EAAC 1,EAAC1,EAAT 3,Excitatory amino acid carrier 1,Excitatory amino acid carrier1,Excitatory amino acid transporter 3,Excitatory amino acid transporter3,Excitatory amino-acid carrier 1,GLUTAMATE TRANSPORTER,HIGH-AFFINITY,MEAAC 1,MEAAC1,Neuronal and epithelial glutamate transporter,REAAC 1,REAAC1,Slc1 a1,Slc1a 1,SLC1A1,Sodium dependent glutamate/aspartate transporter 3,Sodium-dependent glutamate/aspartate transporter 3,Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter,system Xag),member 1,SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER),MEMBER 1,Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter,system Xag),member 1,Solute carrier family 1 member 1,Solute carrier family 1,member 1,SLC1A1抗体 |
| Swissprot | P43005 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human SLC1A1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-2000; |
| Concentration | 0.4mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers). |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. |
