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EBF2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19794

宿主: Rabbit

反应性: H,M

应用: WB

  • 详情
  • Overview

    Synonyms COE 2,COE2,COE2,Collier Olf and EBF 2,Early B cell factor 2,Early B-cell factor 2,EBF 2,EBF-2,Ebf2,FLJ11500,Metencephalon mesencephalnon olfactory transcription factor 1,O/E 3,O/E3,OE 3,OE3,OLF 1/EBF like 3,Transcription factor COE2,EBF2抗体
    Swissprot Q9HAK2
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human EBF2
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 1.68mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
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