ECT2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-53424
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | ECT 2,ECT2 protein,Epithelial cell transforming sequence 2,Epithelial cell transforming sequence 2 oncogene,Epithelial cell transforming sequence 2 oncogene protein,FLJ10461,MGC138291,ECT2抗体 |
Swissprot | Q9H8V3 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human ECT2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:100 |
Concentration | 1.02mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | ECT2 exhibits nuclear localization in interphase, spreads throughout the cytoplasm in prometaphase, and is condensed in the midbody during cytokinesis |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators.The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases.In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver.Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.Several transcript variants encoding different isoforms have been found for this gene. |