ECT2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53424
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | ECT 2,ECT2 protein,Epithelial cell transforming sequence 2,Epithelial cell transforming sequence 2 oncogene,Epithelial cell transforming sequence 2 oncogene protein,FLJ10461,MGC138291,ECT2抗体 |
| Swissprot | Q9H8V3 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human ECT2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:100 |
| Concentration | 1.02mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | ECT2 exhibits nuclear localization in interphase, spreads throughout the cytoplasm in prometaphase, and is condensed in the midbody during cytokinesis |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators.The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases.In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver.Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.Several transcript variants encoding different isoforms have been found for this gene. |
