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ECT2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-53424

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms ECT 2,ECT2 protein,Epithelial cell transforming sequence 2,Epithelial cell transforming sequence 2 oncogene,Epithelial cell transforming sequence 2 oncogene protein,FLJ10461,MGC138291,ECT2抗体
    Swissprot Q9H8V3
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human ECT2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:100
    Concentration 1.02mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization ECT2 exhibits nuclear localization in interphase, spreads throughout the cytoplasm in prometaphase, and is condensed in the midbody during cytokinesis
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators.The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases.In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver.Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.Several transcript variants encoding different isoforms have been found for this gene.
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