EDA Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14972
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | ECTD1,Ectodermal dysplasia 1,anhidrotic,Ectodermal dysplasia protein,Ectodermal dysplasia,anhidrotic (hypohydrotic),Ectodysplasin A,Ectodysplasin A,membrane form,Ectodysplasin A,secreted form,ECTODYSPLASIN A1 ISOFORM,ECTODYSPLASIN A2 ISOFORM,ECTODYSPLASIN,Ectodysplasin-A,ED1 A1,ED1 A2,ED1,ED1 GENE,Eda A1,Eda A2,eda,EDA protein,EDA protein homolog,EDA,EDA1,EDA1 GENE,EDA2,HED,HED1,ODT1,Oligodontia 1,secreted form,STHAGX1,Ta,Tabby,Tabby protein,X linked anhidroitic ectodermal dysplasia protein,XHED,XLHED,EDA抗体 |
| Swissprot | Q92838 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human EDA |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. |
| Tissue specificity | Not abundant; expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. |
