EEF1E1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18404
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | AIMP 3,AIMP3,Aminoacyl tRNA synthetase complex interacting multifunctional protein 3,Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3,ARS interacting multifunctional protein 3,EEF1E1,Elongation factor p18,Eukaryotic translation elongation factor 1 epsilon 1,Eukaryotic translation elongation factor 1 epsilon-1,Homolog of rat elongation factor p18,MCA3,Multisynthase complex auxiliary component p18,Multisynthetase complex auxiliary component p18,p18,p18 component of aminoacyl tRNA synthetase complex,EEF1E1抗体 |
| Swissprot | O43324 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. |
Images
Western blot analysis of 293T cell Hepg2 cell and A431 cell using EEF1E1 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using EEF1E1 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using EEF1E1 Polyclonal Antibody at dilution of 1:35(×200)
