EFNB1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53525
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | CFND,CFNS,Craniofrontonasal syndrome (craniofrontonasal dysplasia),EFL 3,EFL-3,EFL3,EFNB1,EFNB1,Elk L,ELK ligand,ELK-L,Eph related receptor tyrosine kinase ligand 2,EPH-related receptor tyrosine kinase ligand 2,Ephrin-B1,EPLG2,LERK 2,LERK-2,LERK2,Ligand of eph related kinase 2,MGC8782,EFNB1抗体 |
| Swissprot | P98172 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human EFNB1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase. |
