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EGF Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10297

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms Beta urogastrone,beta-urogastrone,EGF,EGF,Epidermal growth factor,HOMG4,OTTHUMP00000219721,OTTHUMP00000219722,Pro epidermal growth factor,URG,Urogastrone,EGF抗体
    Swissprot P01133
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human EGF
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 0.7 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Tissue specificity Expressed in kidney, salivary gland, cerebrum and prostate.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants
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