EGF Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10297
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | Beta urogastrone,beta-urogastrone,EGF,EGF,Epidermal growth factor,HOMG4,OTTHUMP00000219721,OTTHUMP00000219722,Pro epidermal growth factor,URG,Urogastrone,EGF抗体 |
Swissprot | P01133 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant protein of human EGF |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.7 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Tissue specificity | Expressed in kidney, salivary gland, cerebrum and prostate. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants |