EIF4A3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18715
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | ATP-dependent RNA helicase DDX48,ATP-dependent RNA helicase eIF4A-3,DDX48,DEAD box protein 48,eIF-4A-III,eIF4A-III,EIF4A3,eIF4AIII,Eukaryotic initiation factor 4A-III,Eukaryotic initiation factor 4A-like NUK-34,Eukaryotic translation initiation factor 4A isoform 3,hNMP 265,IF4A3,NMP 265,NMP265,Nuclear matrix protein 265,NUK34,EIF4A3抗体 |
| Swissprot | P38919 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human EIF4A3 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
| Concentration | 1.5mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Nucleus speckle. Cytoplasm. Nucleocytoplasmic shuttling protein. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Detected in dendritic layer as well as the nuclear and cytoplasmic (somatic) compartments of neurons. Colocalizes with STAU1 and FMR1 in dendrites. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. |
Images
Western blot analysis of Raji Hela A549 HEPG2 and 231 cell lysates using EIF4A3 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using EIF4A3 Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using EIF4A3 Polyclonal Antibody at dilution of 1:45(×200)
