ELAVL1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10301
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | ELAV (embryonic lethal abnormal vision Drosophila) like 1,ELAV (embryonic lethal,abnormal vision,Drosophila) like 1 (Hu antigen R),ELAV like 1,ELAV like RNA binding protein 1,ELAV-like protein 1,ELAV1,ELAV1,Elavl1,Embryonic lethal abnormal vision drosophila homolog like 1,Hu Antigen R,Hu-antigen R,Hua,HuR,MelG,ELAVL1抗体 |
| Swissprot | Q15717 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human ELAVL1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Tissue specificity | Ubiquitous. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. |
Images
Western Blot analysis of 293T, A431, NIH/3T3, hela and hepG2 cell using ELAVL1 Polyclonal Antibody at dilution of 1:667
Immunohistochemistry of paraffin-embedded Human lung cancer using ELAVL1 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human brain using ELAVL1 Polyclonal Antibody at dilution of 1:40
