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ELMO1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-52186

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms CED 12,Ced 12 homolog 1,Ced 12 homolog,CED-12,CED12,Ced12 homolog 1,Ced12 homolog,ELMO 1,ELMO-1,Elmo1,ELMO1,Engulfment and cell motility 1,Engulfment and cell motility protein 1,KIAA0281,MGC126406,Protein ced-12 homolog,ELMO1抗体
    Swissprot Q92556
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Full length fusion protein
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 0.6mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the engulfment and cell motility protein family.These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration.Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy.Alternative splicing results in multiple transcript variants.
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