EPPIN Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13218
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | Cancer/testis antigen 71,CT 71,CT71,dJ461P17.2,Epididymal protease inhibitor,EPPIN 1,EPPIN 2,EPPIN 3,Eppin,EPPIN1,EPPIN2,EPPIN3,Protease inhibitor WAP7,Serine peptidase inhibitor like with Kunitz and WAP domains 1 (eppin),Serine peptidase inhibitor like with Kunitz and WAP domains 1,SPINLW 1,WAP 7,WAP four disulfide core domain 7,WAP four disulfide core domain protein 7,WAP7,WFDC 7,WFDC7,EPPIN抗体 |
| Swissprot | O95925 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human EPPIN |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Tissue specificity | In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility, and polymorphisms in this gene are associated witHuman, Mouseale infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. |
Images
Western Blot analysis of NIH/3T3 cell, Human testis and Mouse fat tissue using EPPIN Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human liver cancer using EPPIN Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human thyroid cancer using EPPIN Polyclonal Antibody at dilution of 1:25
