ERCC1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19768
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | COFS 4,COFS4,DNA excision repair protein ERCC 1,DNA excision repair protein ERCC-1,DNA excision repair protein ERCC1,ERCC 1,ERCC1,ERCC1,Excision repair cross complementation group 1,Excision repair cross complementing 1,Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1,Excision repair protein,RAD 10,RAD10,UV 20,UV20,ERCC1抗体 |
| Swissprot | P07992 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human ERCC1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11,XPF and ERCC4,which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1,together with RRM1,are determinants of survival after surgical treatment of early-stage,non-small-cell lung cancer. (Ref: Simon,ER. 2005) |
