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Erythropoietin/EPO Monoclonal Antibody(Detector)

规格: / 25μg / 100μg
价格: / ¥800 / ¥2100

货号:AN001970P

货期:咨询

宿主: Rat

反应性: M

应用: ELISA Detector

  • 详情
  • Overview

    Synonyms MGC;ECYT;MVCD;Hematopoietin;Hemopoietin;ECYT5;EP;epoetin;Erythropoietin;MGC138142;MVCD2;Epo
    Swissprot P07321
    Source Rat
    Reactivity Mouse
    Immunogen Recombinant Mouse Erythropoietin/EPO protein expressed by E.coli
    Application ELISA Detector
    Recommended dilution ELISA Detector,,0.1-0.4 μg/mL
    Concentration 1mg/mL
    Clonality Monoclonal

    Properties

    Clone No 7G7
    Isotype IgM
    Purification Protein A/G Purification
    Conjugation Unconjugated
    Storage instructions Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
    Storage buffer Sterile PBS,pH 7.4
    Background This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies.
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