FAAP24 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17929
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | C19ORF40,C19orf40 chromosome 19 open reading frame 40,FAAP24,Fanconi anemia-associated protein 24 kDa,Fanconi anemia-associated protein of 24 kDa,FAP24,MGC32020,FAAP24抗体 |
Swissprot | Q9BTP7 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human FAAP24 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 0.84mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nuclear |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA. |