Factor IX/PTC/F9 Polyclonal Antibody(Capture/Detector)
规格: | / 25μg / 100μg |
价格: | / ¥800 / ¥2100 |
货号:AN001130P
货期:咨询
宿主: Rabbit
反应性: H
应用: ELISA Capture/Detector
Overview
Synonyms | HEMB;P19;PTC;THPH8;Christmas Factor; |
Swissprot | P00740 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant Human Factor IX/PTC/F9 protein expressed by Mammalian |
Application | ELISA Capture/Detector |
Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Storage buffer | Sterile PBS,pH 7.4 |
Background | This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. |