FAN1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17946
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | 6030441H18Rik,Coiled coil domain containing protein MTMR15,DKFZp451H236,DKFZp686K16147,FAN1,FAN1,FANCD2 and FANCI associated nuclease 1,FANCD2/FANCI associated nuclease 1 ,FANCD2/FANCI-associated nuclease 1,Fanconi associated nuclease 1,Fanconi-associated nuclease 1,hFAN1,KIAA1018,KMIN,MTMR 15,MTMR15,Myotubularin related protein 15,Myotubularin-related protein 15,FAN1抗体 |
| Swissprot | Q9Y2M0 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human FAN1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity.Mutations in this gene cause karyomegalic interstitial nephritis.Alternatively spliced transcript variants encoding distinct isoforms have been described. |
