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FANCG Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-11217

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms DNA repair protein XRCC9,FAG,FANCG,FANCG,Fanconi anaemia complementation group G,Fanconi anemia group G protein,Protein FACG,X ray repair,complementing defective,in Chinese hamster cells 9,X-ray repair,complementing defective,in Chinese hamster,9,XRCC9,FANCG抗体
    Swissprot O15287
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human FANCG
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 1 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
    Tissue specificity Highly expressed in testis and thymus. Found in lymphoblasts.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
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