FAS/CD95 Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：D-AB-10418L
货期：咨询
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | ALPS1A,APO 1,Apo 1 antigen,APT1,CD95,FAS,FAS/CD95,FAS1,FASLG receptor,FASTM,TNFRSF6 |
| Swissprot | P25445 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human FAS/CD95 protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:250-1:500; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The molecular mass of native Fas is 38 kDa,the high molecular weight form (40-55 kDa) of Fas is due to glycosylation. |
