FBXW8 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17953
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | F box and WD40 domain containing protein 8,F box only protein 29,F box/WD repeat containing protein 8,F-box and WD-40 domain-containing protein 8,F-box only protein 29,F-box/WD repeat-containing protein 8,FBW6,FBW8,FBX29,FBXO29,FBXW6,FBXW8,FBXW8,FBXW8抗体 |
| Swissprot | Q8N3Y1 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human FBXW8 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 1.92mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
